EIPH Research Unveils Possible 24-Hour Furosemide Dose

Emphasis placed on strategies to control EIPH without race-day medication

Two research projects on Exercise Induced Pulmonary Hemorrhage solicited by The Grayson-Jockey Club Research Foundation and funded in cooperation with The Jockey Club, the AAEP Foundation, Keeneland Association, Oak Tree Racing Association, The Stronach Group, Churchill Downs, Kentucky Downs, New York Racing Association, The Del Mar Thoroughbred Club, Oaklawn Park, and The Thoroughbred Horseman’s Association have now appeared in peer-reviewed journals.

Knych HK, Wilson WD, Vale A, et al.
Effectiveness of furosemide in attenuating exercise-induced pulmonary haemorrhage in horses when administered 4- and 24-h prior to high speed training. Equine Vet J. 2017;50:350-355.

Bayly W, Lopez C, Sides R, et al.
Effect of different protocols on the mitigation of exercise induced pulmonary hemorrhage in horses when administered 24 hours before strenuous exercise. J Vet Intern Med. 2019; 1–8. https://doi.org/10.1111/jvim.15574

In March 2015, a special call for research on exercise induced pulmonary hemorrhage was issued by The Grayson-Jockey Club Research Foundation. Emphasis was placed on strategies to control EIPH without race-day medication. Two projects were selected. The premise of the research was to look at the post-treatment effect of furosemide (Salix, or Lasix) if it had been given 24 hours before exercise with water intake limited to maintenance water levels (which are known).

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